Paid
SERVICE DESCRIPTION | • Antidiabetic with α-glucosidase inhibition methods Ø Method: Dewi, R.T., Tachibana, S., Darmawan, A., Effects on a-glucosidase inhibition and antioxidant activities of butyrolactone derivatives from Aspergillus terreus MC75, Med Chem Res.…
- Laboratorium Cara Pembuatan Obat Tradisional yang Baik (CPOTB)
- Puspiptek - Serpong
Laboratorium Cara Pembuatan Obat Tradisional yang Baik (CPOTB) Gedung 450 Kawasan Sains dan Teknologi BJ. Habibie (PUSPIPTEK) Serpong, 15314, Tangerang Selatan, Banten – Indonesia - 08119811565
- labcpotb@brin.go.id
Marketing Office
Deputi Bidang Infrastruktur Riset dan Inovasi BRIN
layanan_sains@brin.go.id
• Antidiabetic with α-glucosidase inhibition methods
Ø Method: Dewi, R.T., Tachibana, S., Darmawan, A., Effects on a-glucosidase inhibition and antioxidant activities of butyrolactone derivatives from Aspergillus terreus MC75, Med Chem Res. 23: 454–460. 2014. DOI 10.1007 / s00044-013-0659-4.
Ø Prinsif action: The mechanism of the a-glucosidase reaction is to catalyze the reaction of the breakdown of the substrate into p-nitrophenol and glucose. The substrate used was p-nitrophenyl-a-D-glucopyranoside, at 370C. The activity of this enzyme is measured based on the uptake of p-nitrophenol produced. If the sample has the ability to inhibit the activity of uk-glucosidase, the p-nitrophenol produced will be reduced.
Enzim In vitro enzymatic methods for testing the ability of a-glucosidase activity are a cheaper and faster alternative to initial screening, and then only extracts that are truly potentially tested by in vivo methods in experimental animals.
Application Requirements:
Ø Method: Dewi, R.T., Tachibana, S., Darmawan, A., Effects on a-glucosidase inhibition and antioxidant activities of butyrolactone derivatives from Aspergillus terreus MC75, Med Chem Res. 23: 454–460. 2014. DOI 10.1007 / s00044-013-0659-4.
Ø Prinsif action: The mechanism of the a-glucosidase reaction is to catalyze the reaction of the breakdown of the substrate into p-nitrophenol and glucose. The substrate used was p-nitrophenyl-a-D-glucopyranoside, at 370C. The activity of this enzyme is measured based on the uptake of p-nitrophenol produced. If the sample has the ability to inhibit the activity of uk-glucosidase, the p-nitrophenol produced will be reduced.
Enzim In vitro enzymatic methods for testing the ability of a-glucosidase activity are a cheaper and faster alternative to initial screening, and then only extracts that are truly potentially tested by in vivo methods in experimental animals.
Application Requirements:
- Photo
- Other Supporting File
| File Name | File Size | |
|---|---|---|
| Service SOP file | 0.44 MB | |
| Template Photo | 0 MB | |
| Template Other Supporting File | 0 MB |
